Abc1 polypeptide and methods and reagents for modulating...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01) A01K 67/027 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2367955

The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).

L'invention se rapporte à des acides nucléiques et à des polypeptides ABC1 permettant de diagnostiquer et de traiter une régulation anormale du cholestérol. Elle se rapporte également à des méthodes d'identification de composés permettant de moduler les taux de cholestérol chez un animal (par exemple, un humain).

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