Abca1 elevating compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 491/04 (2006.01) A61K 31/4741 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2672428

The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCAl production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.

La présente invention concerne des composés utiles pour augmenter la production de transporteur de cassette de liaison à l'ATP cellulaire ABCA1 chez des mammifères, et des procédés d'utilisation de tels composés dans le traitement de maladies coronariennes, de dyslipidémies et du syndrome métabolique. L'invention concerne également des procédés de préparation de tels composés, et des compositions pharmaceutiques les contenant.

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