C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/04 (2006.01) A61K 31/436 (2006.01) A61P 9/10 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2613703
The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCAl production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
La présente invention concerne des composés pouvant être employés pour augmenter la production du transporteur ABCA1 (ATP-Binding-Cassette A1) chez les mammifères, ainsi que des méthodes d'emploi de tels composés dans le traitement de maladies coronariennes, de dyslipidémies et du syndrome métabolique. La présente invention concerne également des méthodes de synthèse de tels composés et des préparations pharmaceutiques les contenant.
Abelman Matthew
Jiang Robert
Koltun Dmitry
Zablocki Jeff
Cv Therapeutics Inc.
Gilead Palo Alto Inc.
Mbm Intellectual Property Law Llp
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