C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/04 (2006.01) A61K 31/4535 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2707718
The present invention relates to a breast cancer resistance protein (BCRP/ABCG2) inhibitor. The invention provides an acrylonitrile derivative represented by formula (1): (see formula 1) (wherein A represents an optionally substituted 3- to 8- membered heterocyclic ring) or a salt thereof.
L'invention porte sur un inhibiteur de la protéine de résistance du cancer du sein (BCRP/ABCG2). De façon spécifique, l'invention porte sur un dérivé d'acrylonitrile représenté par la formule générale (1) ou un sel de celui-ci. [Dans la formule, A représente un noyau hétérocyclique à 3 à 8 chaînons facultativement substitué.]
Hatano Hiroshi
Igarashi Yoshiaki
Sugimoto Yoshikazu
Yaegashi Takashi
Yamazaki Ryuta
Kabushiki Kaisha Yakult Honsha
Smart & Biggar
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