Absorbable composite materials for use in the treatment of...

A - Human Necessities – 61 – K

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A61K 9/70 (2006.01) A61K 6/00 (2006.01) A61K 9/00 (2006.01) A61L 27/00 (2006.01) A61L 27/48 (2006.01) A61L 27/50 (2006.01) A61L 31/12 (2006.01) A61L 31/14 (2006.01) A61F 2/02 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2129051

Absorbable composite materials are described that comprise a collagen matrix reinforced with a layer of a biaabsorbable polymer. A chemotherapeutic agent is dispersed in the composite material. The layer of bioabsorbable polymer is preferably a woven, nonwoven or knitted mesh layer of a synthetic bioabsorbable polymer such as polylactic/polyglycolic acid copolymer, or oxidised regenerated cellulose. The chemotherapeutic agent may be an antibiotic, an anaesthetic, an antiseptic or an anti-inflammatory. Strips of the composite material are inserted into the periodontal pocket, where they are retained in place and provide effective sustained release of the chemotherapeutic agent over an extended period.

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