Absorbable pharmaceutical compositions based on isomorphic...

A - Human Necessities – 61 – K

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A61K 31/74 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 31/56 (2006.01) C08G 63/18 (2006.01)

Patent

CA 1100041

ABSTRACT Absorbable copolyoxalate polymers having isomorphic sequences are formulated with drugs and introduced into the body to provide a slow, sustained release of the drug over an extended period of time in accordance with the rate of absorp- tion of the polymer. The copolyoxalate polymers are derived from mixtures of cyclic and linear diols, each having the same number of carbon atoms. The polymers are biodegradable in animal tissue and absorb with minimal adverse tissue reaction.

304043

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