Absorbent polymeric compositions with varying counterion...

A - Human Necessities – 61 – L

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A61L 15/60 (2006.01) C08F 8/00 (2006.01) C08F 20/00 (2006.01)

Patent

CA 2697803

Cross-linked polyelectrolyte polymers with bound counterions that absorb about 20-fold or more of their mass in saline such as physiological saline a with the proviso that sodium does not exceed 60% of total bound counterions when hydrogen is the sole other counterion, are disclosed. Methods of preparing the disclosed polymers and for treating subjects such as patients in need of fluid removal and/or modulation of ions (e.g., sodium and/or potassium) are provided.

L'invention concerne des polymères polyélectrolytiques réticulés à contre-ions liés qui absorbent environ 20 fois, voire plus, leur masse en solution saline, par exemple une solution saline physiologique, pour autant que le sodium n'excède pas 60% du total des contre-ions liés lorsque l'hydrogène est le seul autre contre-ion. L'invention concerne également des procédés permettant de préparer ces polymères et de traiter des patients qui nécessitent le retrait de liquide et/ou la modulation des ions (par exemple du sodium et/ou du potassium).

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