Abuse-resistant opioid dosage form

Details Abuse-resistant opioid dosage form Abuse-resistant opioid dosage form

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61K 31/00 (2006.01) A61K 31/137 (2006.01) A61K 31/444 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2486095

The present invention pertains to a pharmaceutical dosage form comprising an opioid analgesic and a nontoxic N-methyl-D-aspartate receptor antagonist wherein the pharmaceutical dosage form is substantially free of an opioid antagonist. The nontoxic N-methyl-D-aspartate receptor antagonist is present in an opioid euphoria-inhibiting amount to prevent or discourage abuse.

L'invention concerne une forme posologique pharmaceutique comprenant un analgésique opioïde et un antagoniste du récepteur N-méthyl-D-aspartate non toxique, qui est sensiblement dépourvue d'un antagoniste opioïde. Ledit antagoniste du récepteur N-méthyl-D-aspartate non toxique est présent à une dose empêchant un sentiment d'euphorie provoqué par un opioïde afin de prévenir ou de décourager une utilisation abusive.

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