Abuse resistant pharmaceutical composition containing capsaicin

Details Abuse resistant pharmaceutical composition containing capsaicin Abuse resistant pharmaceutical composition containing capsaicin

A - Human Necessities

61

K

A61K 31/165 (2006.01) A61K 31/485 (2006.01) A61K 45/06 (2006.01) A61P 25/36 (2006.01)

Patent

CA 2447807

A pharmaceutical composition intended for oral use contains the effective ingredient(s), capsaicin, and other typical fillers and excipients. The composition is preferably in the form of a solid oral dosage form. Transdermally administered compositions are also within the purview of the invention. Aside from the effective pharmaceutical ingredient(s) the composition includes an amount of capsaicin which serves as a deterrent to the intranasal, intravenous, or oral abuse of the composition. Such a composition deters abusers from crushing prescription pharmaceutical tablets for abusive snorting, injection, or ingestion.

Cette invention se rapporte à une composition pharmaceutique destinée à une administration par voie orale et contenant comme principe actif de la capsaïcine, ainsi que d'autres charges et excipients typiques. Cette composition est de préférence produite en formes posologiques solides à administration par voie orale. De telles compositions à administrer par voie transdermique sont également du ressort de cette invention. Outre le principe actif pharmaceutique, cette composition contient une certaine quantité de capsaïcine qui a une fonction dissuasive contre tout abus intranasal, intraveineux ou oral de la composition. Une telle composition dissuade ainsi toute personne qui voudrait en abuser de concasser les comprimés pharmaceutiques prescrits pour en abuser par reniflage, injection ou ingestion.

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