C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2567980
Human ACAC genes are identified as modulators of the IGF pathway, and thus are therapeutic targets for disorders associated with defective IGF function. Methods for identifying modulators of IGF, comprising screening for agents that modulate the activity of ACAC are provided.
L'invention concerne des gènes ACAC humains identifiés comme modulateurs de la voie IGF, puis comme cibles thérapeutiques pour des troubles associés à une fonction IGF déficiente. L'invention décrit des procédés permettant d'identifier des modulateurs d'IGF et comprend le criblage d'agents modulant l'activité des ACACS.
Bjerke Lynn Margaret
Heuer Timothy S.
Maxwell Mark E.
Ollmann Michael Martin
Bennett Jones Llp
Exelixis Inc.
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