Acarbose methods and formulations for treating chronic...

A - Human Necessities – 61 – K

Patent

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A61K 31/715 (2006.01) A61P 1/10 (2006.01)

Patent

CA 2599063

The present invention is directed to a method for treating chronic constipation in a subject in need of such treatment comprising administering to the subject a dosage formulation comprising a therapeutically effective amount of acarbose, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable ingredient to control the release of the acarbose, wherein following administration, the dosage formulation releases the acarbose distal to the gastrointestinal sites at which acarbose is absorbed.

La présente invention concerne un procédé permettant de traiter la constipation chronique chez un sujet justifiant d'un tel traitement. La posologie comprend une quantité thérapeutiquement suffisante d'acarbose, ou de l'un de ses sels pharmaceutiquement admis. On associe à l'acarbose au moins un agent pharmaco-compatible régulant sa libération. Il en résulte qu'après administration, la formulation posologique libère l'acarabose loin des sites gastro-intestinaux d'absorption.

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