Acat inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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167/179, 260/283

C07C 275/28 (2006.01) A61K 31/00 (2006.01) C07D 209/42 (2006.01) C07D 213/00 (2006.01) C07D 213/42 (2006.01) C07D 213/81 (2006.01) C07D 215/48 (2006.01) C07D 215/60 (2006.01) C07D 241/24 (2006.01) C07D 307/52 (2006.01) C07D 307/54 (2006.01) C07D 307/68 (2006.01) C07D 333/20 (2006.01) C07D 333/24 (2006.01)

Patent

CA 2029338

ABSTRACT This invention relates to novel compounds which are ACAT inhibitors rendering them useful in lowering blood cholesterol levels. The compounds contain two urea or thiourea, amide, or amine moieties or combinations of said moieties and have the following general formula: Image wherein Ar is an aryl group, m and n are zero or one, W and YNH and Image form the urea, thiourea, amide or amine moieties.

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