Accelerated release composition containing bromocriptine

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/495 (2006.01) A61K 9/20 (2006.01) A61K 31/00 (2006.01) A61K 31/475 (2006.01) A61K 31/48 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2179540

Disclosed herein is a solid oral dosage form comprising bromocriptine and one or more pharmaceutically acceptable excipients. The oral dosage form has a dissolution rate in excess of 90 % in 5 minutes in 500 ml of 0.1N HC? aqueous medium at 37 °C and is useful for adjusting the plasma prolactin profile of a patient.

L'invention concerne une forme galénique orale solide comprenant de la bromocryptine ainsi que un ou plusieurs excipients pharmaceutiquement acceptables. La forme galénique orale présente une vitesse de dissolution supérieure à 90 % en 5 minutes dans 500 ml d'un milieu aqueux de 0,1N HCl à 37 ~C, elle est utile pour régler le profil de prolactine plasmatique d'un patient.

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