Accelerators for forming cationic technetium complexes...

Details Accelerators for forming cationic technetium complexes... Accelerators for forming cationic technetium complexes...

A - Human Necessities

61

K

31/2, 167/48

A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07F 9/70 (2006.01) C07F 13/00 (2006.01)

Patent

CA 1187790

ABSTRACT A composition for preparing cationic lipophilic technetium complexes for radiodiagnostic imaging, particularly in heart imaging comprises an admixture of (a) an accelerator compound selected from the group of water-soluble organic bidentate ligands that are capable of coordinating with technetium to form a 4 to 6 r. ?r ring and (b) a target-seeking ligand or aqueous salt thereof, having the following structure: Image wherein the variants can be selected from a variety of values; the composition is suitably provided as a kit of lyophilized solids in a pre-sterilized vial.

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