Acellular matrix grafts: preparation and use

Details Acellular matrix grafts: preparation and use Acellular matrix grafts: preparation and use

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61K 35/22 (2006.01) A61L 27/26 (2006.01) A61L 27/36 (2006.01) A61F 2/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2309158

Acellular matrix grafts are provided which are isolated from natural sources and consist essentially of a collagen and elastin matrix which is devoid of cellular components. The grafts are useful scaffold which promote the regeneration of muscle tissue and aid in restoring muscle function. Due to their acellular nature, the grafts lack antigenicity. As a result, the acellular matrix grafts can be isolated from autographic, allographic or xenographic tissues.

L'invention concerne des greffons matriciels acellulaires qui sont isolés à partir de sources naturelles et constitués essentiellement d'une matrice de collagène et d'élastine sensiblement dépourvue d'éléments cellulaires. Ces greffons sont des supports utiles, qui favorisent la régénération du tissu musculaire et contribuent à restaurer la fonction musculaire. De par leur nature acellulaire, ils sont dépourvus de caractère antigénique. Ils peuvent donc être isolés à partir de tissus autologues, allogéniques ou xénogéniques.

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