Acellular pertussis vaccine with diphtheria- and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/10 (2006.01) A61K 39/05 (2006.01) A61K 39/08 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2271008

The invention provides a diphtheria, tetanus and pertussis vaccine comprising a low dose of each of diphtheria toxoid (D), tetanus toxoid (T), pertussis toxin (PT), filamentous haemagglutinin (FHA) and pertactin (69K). The vaccine maintains an ability to prevent pertussis while showing exceptionally low reactogenicity. Combination vaccines comprising additional antigens are also provided.

L'invention concerne un vaccin antidiphtérique, antitétanique et anticoquelucheux, qui comprend une faible dose d'anatoxine diphtérique (D), d'anatoxine tétanique (T), d'anatoxine coquelucheuse (PT), d'hémagglutinine filamenteuse (FHA) et de pertactine (69K). Ledit vaccin maintient une aptitude à empêcher l'apparition de la coqueluche chez un sujet tout en présentant une réactogénicité exceptionnellement faible. L'invention concerne également des vaccins de combinaison qui contiennent des antigènes additionnels.

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