Acetic acid derivatives

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/00 (2006.01) A01N 43/40 (2006.01) A61K 31/195 (2006.01) A61K 31/24 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 38/00 (2006.01) A61K 38/04 (2006.01) C07C 237/20 (2006.01) C07C 237/36 (2006.01) C07C 257/18 (2006.01) C07C 257/20 (2006.01) C07D 207/00 (2006.01) C07D 207/04 (2006.01) C07D 207/09 (2006.01) C07D 207/16 (2006.01) C07D 211/34 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 295/185 (2006.01) C07D 295/192

Patent

CA 2037153

RAN 4045/12 Abstract Acetic acid derivatives of the formula H2N(NH)C-X-Y-CO-CH(Q1)COOQ2 I in which X, Y, Z, Q1 and Q2 have the meaning indicated in the description, and hydrates, solvates and physiologically utilisable salts thereof inhibit the binding of adhesive proteins to blood platelets and also inhibit blood platelet aggregation and cell-cell adhesion. They are prepared by removal of protecting groups in appropriate compounds containing ester groups and protected amidino groups.

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