C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 235/24 (2006.01) A61K 31/16 (2006.01) A61K 31/33 (2006.01) A61P 3/00 (2006.01) A61P 7/00 (2006.01) C07C 323/62 (2006.01) C07C 323/63 (2006.01) C07C 327/42 (2006.01) C07D 207/273 (2006.01) C07D 209/48 (2006.01) C07D 213/64 (2006.01) C07D 239/38 (2006.01) C07D 257/04 (2006.01) C07D 271/06 (2006.01) C07D 317/64 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2493457
Novel acetylamino benzoic acid compounds, methods of using and pharmaceutical compositions comprising an acetylamino benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
L'invention concerne de nouveaux composés d'acide acétyl amino benzoïque, des procédés d'utilisation d'un dérivé d'acide acétyl amino benzoïque et des compositions pharmaceutiques comprenant ce dernier. Il s'agit notamment de procédés de traitement ou de prévention d'une maladie qui sont améliorés par la modulation de la terminaison de translation prématurée ou la dégradation de l'ARNm médiée par les non-sens, ou qui améliorent au moins un symptôme qui y est associé.
Almstead Neil G.
Beckmann Holger
Rubenstein Steven Marc
Takasugi James Jan
Welch. Ellen M.
Osler Hoskin & Harcourt Llp
Ptc Therapeutics Inc.
Tularik Inc.
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