Acetylene derivatives and methods for the treatment of...

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C - Chemistry, Metallurgy

07

C

167/207, 167/276

C07C 205/32 (2006.01) C07C 17/00 (2006.01) C07C 45/58 (2006.01) C07C 45/62 (2006.01) C07C 45/63 (2006.01) C07C 45/68 (2006.01) C07C 45/74 (2006.01) C07C 49/255 (2006.01) C07C 51/363 (2006.01) C07C 59/64 (2006.01) C07C 217/62 (2006.01) C07D 295/096 (2006.01) C07D 295/185 (2006.01) C07D 303/40 (2006.01) C07D 317/58 (2006.01) C07D 317/62 (2006.01)

Patent

CA 1242718

ACETYLENE DERIVATIVES AND METHODS FOR THE TREATMENT OF HYPERTENSION AND ANGINA Abstract Acetylene compounds of the formula (I): (I) Image wherein Y, R1, R2 R3, and R4 are as described herein, m is 0-3, n is 0-2 and Ar is phenyl or an aromatic heterocycle are disclosed. The compounds possess anti-hypertensive and anti-anginal properties and may be used in the treatment of humans. Methods for the preparation and use of such acetylene compounds are also disclosed.

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