Acetylene derivatives and their use for binding and imaging...

Details Acetylene derivatives and their use for binding and imaging... Acetylene derivatives and their use for binding and imaging...

C - Chemistry, Metallurgy

07

D

C07D 213/64 (2006.01) A61K 31/05 (2006.01) A61K 31/136 (2006.01) A61K 31/44 (2006.01) A61P 25/28 (2006.01) C07C 43/178 (2006.01) C07C 43/225 (2006.01) C07C 43/295 (2006.01) C07C 217/48 (2006.01) C07D 213/74 (2006.01)

Patent

CA 2672187

The invention relates to radiolabeled compounds and their use in methods of imaging amyloid deposits, as well as to methods of their manufacture. The invention also relates to compounds for inhibiting the aggregation of amyloid proteins that form amyloid deposits, methods for delivering therapeutic agents to amyloid deposits, as well as methods of making compounds that inhibit the aggregation of amyloid proteins.

Composés radiomarqués et leur utilisation avec des méthodes de représentation de dépôts amyloïdes, ainsi que leurs procédés d'obtention. L'invention concerne également des capables d d'inhiber l'agrégation de protéines amyloïdes formant des dépôts amyloïdes, des méthodes d'administration d'agents thérapeutiques à ces dépôts, et des méthodes de fabrication de composés qui inhibent l'agrégation de protéines amyloïdes

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