Acetylene derivatives as anti-inflammatory/analgesic agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61K 31/4439 (2006.01) A61K 31/495 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) C07D 231/14 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/10 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2326970

The present invention relates to compounds of the formula (see formula I) wherein R1, R2, R3, R4, R5, R6, X and Y are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock.

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