Acetylene derivatives as inhibitors of histone deacetylase

Details Acetylene derivatives as inhibitors of histone deacetylase Acetylene derivatives as inhibitors of histone deacetylase

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/343 (2006.01) A61P 35/00 (2006.01) C07C 259/10 (2006.01) C07D 215/48 (2006.01) C07D 239/70 (2006.01) C07D 277/56 (2006.01) C07D 307/85 (2006.01) C07D 333/70 (2006.01)

Patent

CA 2535350

The present invention is directed to certain hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.

La présente invention a trait à certains dérivés d'hydroxamate qui sont des inhibiteurs d'histone déacétylase et donc utiles dans le traitement de maladies associées à l'activité d'histone déacétylase. L'invention a également trait à des compositions pharmaceutiques et des procédés pour la préparation desdits composés.

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