Acetylene derivatives having mglur5 antagonistic activity

Details Acetylene derivatives having mglur5 antagonistic activity Acetylene derivatives having mglur5 antagonistic activity

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/404 (2006.01) A61K 31/4709 (2006.01) A61P 25/00 (2006.01) C07C 233/23 (2006.01) C07C 271/16 (2006.01) C07C 271/24 (2006.01) C07D 209/08 (2006.01) C07D 209/32 (2006.01) C07D 209/44 (2006.01) C07D 215/20 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2466560

The invention provides compounds of formula (I) wherein m, n, A, R, R', R", Ro, X and Y are as defined in the description, and their preparation. The compounds of formula (I) are useful as pharmaceuticals in the treatment of e.g. nervous system disorders.

L'invention concerne des composés représentés par la formule (I) dans laquelle m, n, A, R, R', R'', R¿o?, X et Y sont tels que définis dans la description. L'invention concerne également leur préparation. Les composés représentés par la formule (I) sont utiles en tant que médicaments, notamment dans le traitement de troubles du système nerveux.

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