Acetylsalicylic acid thioesters, a process for their...

Details Acetylsalicylic acid thioesters, a process for their... Acetylsalicylic acid thioesters, a process for their...

C - Chemistry, Metallurgy

07

H

260/471.1

C07H 17/08 (2006.01)

Patent

CA 1202317

ABSTRACT OF THE DISCLOSURE This invention discloses novel acetylsalicylic acid thioesters of the formula (I) Image (I) wherein n is 0 or 1, R1 is hydrogen, methyl or carboxy and R2 is hydrogen or an acetamido group. These compounds are prepared by reactîng a functional derivative of acetylsalicylic acid with a suitable thiol. Pharmaceutical composition having these compounds as active ingredients have improved antipyretic activity and are useful for the symptomatic treatment of influenza.

436108

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