Achromobacter protease i gene and gene product thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

195/39, 195/1.22

C12N 15/57 (2006.01) C12N 9/52 (2006.01)

Patent

CA 2011378

TITLE: ACHROMOBACTER PROTEASE I GENE AND GENE PRODUCT THEREOF ABSTRACT Disclosed are a DNA sequence containing a DNA segment coding for Achromobacter protease I (API) or an analog thereof (they are referred as T-API); a recombinant DNA constructed by introducing the DNA sequence in an expression vector so as to express the T-API; a transformant bearing the recombinant DNA; a process for producing the API which comprises cultivating the transformant, accumulating the T-API in a culture product, and recovering the same; and a protein of T-API. The cells transfected or transformed with the DNA sequence of the present invention can allow a large amount of the precursor protein of the T-API or the mature peptide to be produced.

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