Acid and ester derivatives of vinblastine, vincristine and...

Details Acid and ester derivatives of vinblastine, vincristine and... Acid and ester derivatives of vinblastine, vincristine and...

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1061785

Abstract The invention relates to 3-carboxylic acids and esters and 4-desacetyl-3-carboxylic acids and esters of vinblastine, vincristine and leurosidine and to processes for the preparation thereof by reacting vinblastine, vin- cristine or leurosidine with dilute base to form the 4- desacetyl acid and if desired acetylating the thus formed acid.

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