A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/06 (2006.01) A61K 9/10 (2006.01) A61P 5/48 (2006.01)
Patent
CA 2697034
The present invention relates to compositions forming a low viscosity mixture of: i) a non-polymeric slow-release matrix ii) at least one biocompatible, (preferably oxygen containing) organic solvent; iii) at least one peptide active agent; and iv) at least one lipid soluble acid. The invention further relates to methods of treatment comprising administration of such compositions, especially in treating diabetes, and to pre-filled administration devices and kits containing the formulations.
La présente invention porte sur des compositions formant un mélange à faible viscosité de : 1) une matrice à libération lente non polymère; ii) au mois un solvant organique (de préférence contenant de l'oxygène), biocompatible; iii) au moins un agent actif peptidique; et iv) au moins un acide soluble dans les lipides. L'invention porte en outre sur des procédés de traitement comprenant l'administration de telles compositions, notamment pour traiter le diabète, et sur des dispositifs d'administration pré-remplis et sur des coffrets contenant les formulations.
Johnsson Markus
Nistor Catalin
Tiberg Fredrik
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Camurus Ab
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