A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/282 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2537170
There is provided a pharmaceutical liquid formulation of oxaliplatin for parenteral administration, said formulation comprising (i) oxaliplatin; (ii) water; and (iii) an acid wherein the acid is stabilising and is not malonic acid, lactic acid or oxalic acid. Methods of preparing the formulation are also disclosed. There is further provided the use of the formulation in the preparation of a medicament for the treatment of cancer and a method for treating cancer which comprises administering a therapeutic amount of a pharmaceutical formulation.
L'invention concerne une formulation liquide pharmaceutique destinée à une administration parentérale. Cette formulation comprend : (i) de l'oxaliplatine ; (ii) de l'eau ; et (iii) un acide, l'acide étant un stabilisant et n'étant pas de l'acide malonique, de l'acide lactique ou de l'acide oxalique. L'invention concerne également des procédés de préparation de la formulation. L'invention concerne en outre l'utilisation de ladite formulation dans la préparation d'un médicament destiné au traitement du cancer et un procédé de traitement du cancer qui consiste à administrer une dose thérapeutique d'une formulation pharmaceutique.
Liu Aikun Julie
Whittaker Darryl Vanstone
Macera & Jarzyna Llp
Mayne Pharma Limited
Mayne Pharma Pty Ltd
LandOfFree
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