Acid salts of l-(cyanoalkyl)-4-guanylpiperazines and methods...

Details Acid salts of l-(cyanoalkyl)-4-guanylpiperazines and methods... Acid salts of l-(cyanoalkyl)-4-guanylpiperazines and methods...

C - Chemistry, Metallurgy

07

D

260/263, 260/267

C07D 295/20 (2006.01) C07D 239/42 (2006.01) C07D 295/215 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01)

Patent

CA 1250581

-i- ACID SALTS OF 1-(CYANOALKYL)-4 GUANYLPIPERAZINES AND METHODS FOR THEIR PREPARATION AND USE Abstract Novel 1-(cyanoalkyl)-4-guanylpiperazine acid salts are prepared by reacting novel 1-(cyanoalkyl)piperazines with cyanamide in the presence of an acid. The novel 1-(cyanoalkyl)-4- guanylpiperazine acid salts are advantageously employed to prepare 1-(cyanoalkyl)-4-(2- pyrimidyl)piperazines by reacting them with malonaldehyde in an acidic medium.

432556

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