Acne lesions biomarkers and modulators thereof

Details Acne lesions biomarkers and modulators thereof Acne lesions biomarkers and modulators thereof

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2635650

The present invention relates to acne lesions biomarkers/ genes expression products pattern and particularly inflammatory acne lesions biomarkers and their uses, modulators thereof and the use of modulators for acne treatment or associated disorders. Invention also concerns in vitro diagnostic methods. Gene array expression profiling reveiled a prominent role of matrix metalloproteinases, inflammatory cytokines anti-microbial peptides in acne lesions.

La présente invention concerne un schéma à base de biomarqueurs de lésions acnéiques/produits d'expression génique, en particulier des biomarqueurs de lésions acnéiques inflammatoires, ainsi que leurs utilisations, leurs modulateurs et l'utilisation de modulateurs pour le traitement de l'acné ou de troubles associés. L'invention concerne également des procédés de diagnostic in vitro.

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