Acridinium compound having a plurality of luminescent groups...

Details Acridinium compound having a plurality of luminescent groups... Acridinium compound having a plurality of luminescent groups...

C - Chemistry, Metallurgy

07

D

C07D 219/04 (2006.01) C07D 401/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C09K 11/07 (2006.01) C12N 9/96 (2006.01) G01N 33/533 (2006.01)

Patent

CA 2182457

Acridinium compounds and their conjugates exhibiting high chemiluminescence yield are provided. Such compounds may be used to enable a highly sensitive specific binding assay. The acridinium compounds are represented by formula (I): Image (I) wherein A is a linker; Z is a binding group; Y is a counter ion; R1 and R2 are independently a substituent; p and m are independently an integer of from 0 to 4; n is an integer of from 2 to 5; and X is an organic intervening moiety with a functionality of at least n, having an aryloxy group or an arylsulfonamide group throllgh which X binds to carbonyl carbon bonded to 9-position of the acridinium ring.

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