Acridinium compounds as chemiluminogenic label

C - Chemistry – Metallurgy – 07 – D

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260/282, 167/43

C07D 219/04 (2006.01) C09K 11/07 (2006.01) G01N 33/533 (2006.01)

Patent

CA 1334418

New acridinium compounds are provided which comply with formula 1: Image wherein, A is a divalent organic moiety, such as an alkylene chain, X is a group which can be transformed together with C-9 of the acridine into a dioxetane by reaction with hydrogen peroxide, such as an aryloxy group, Y is a counter ion, and Z is a functional group, such as a carboxyl derivative. These acridinium compound are useful as chemiluminogenic labels for both heterogeneous and homogeneous immunoassays.

586045

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