Acrolein microspheres

Details Acrolein microspheres Acrolein microspheres

C - Chemistry, Metallurgy

08

L

31/121, 400/9057

C08L 29/00 (2006.01) H01F 1/28 (2006.01)

Patent

CA 1218185

ACROLEIN MICROSPHERES ABSTRACT Microspheres of acrolein homopolymers and co- polymer with hydrophillic comonomers such as methacrylic acid and/or hydroxyethylmethacrylate are prepared by cobalt gamma irradiation of dilute aqueous solutions of the monomers in presence of suspending agents, especially alkyl sulfates such as sodium dodecyl sulfate. Amine or hydroxyl modification is achieved by forming adducts with diamines or alkanol amines. Carboxyl modification is effected by oxidation with peroxides. Pharmaceuticals or other aldehyde reactive materials can be coupled to the microspheres. The microspheres directly form antibody adducts without agglomeration.

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