Acrylic derivatives of piperazine, the method of preparing...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/18 (2006.01) C07D 295/185 (2006.01) C07D 317/60 (2006.01) C07D 319/18 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01)

Patent

CA 1246076

Title : "New arylic derivatives of piperazine, the method of preparing same and their application in therapeutics" (Invention of Alain PLATEL, Alain LACOUR, Guy BOURGERY) Applicant : DELALANDE S.A. ABSTRACT OF THE DISCLOSURE New derivatives are provided corresponding to the formula : Image (I) in which Ar represents an aromatic nucleus ; and X represents : - either the trans -?H=?H-?O- chain or the -?H2-?H2-?O- chain and A = COnHOH, COOEt, COOH or CONR2R3, - either the trans-CH=CH-CH2- chain or -CH2-CH2-CH2 chain and A = carboxamido, N-isopropylcarboxamido, pyrrolidinocarbonyl or piperidinocarbonyl. These derivatives and their salts are used as drug for their activity stimulating, protecting and/or correcting cerebral functions.

422056

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