Acrylic microchannels and their use in electrophoretic...

G - Physics – 01 – N

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G01N 27/453 (2006.01) C12Q 1/68 (2006.01) G01N 27/447 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2249886

Microchannels having at least an acrylic inner surface and methods of their use in electrophoretic applications are provided. The subject microchannels may be in the form of a variety of configurations suitable for holding an electrophoretic medium. The subject microchannels give rise to substantially reduced EOF and/or adsorption as compared to fused silica under conditions of electrophoresis and find use in a variety of electrophoretic applications in which charged entities are moved through a medium under the influence of an applied electric field.

L'invention concerne des microcanaux ayant au moins une surface interne acrylique et leur utilisation dans des applications électrophorétiques. Les microcanaux en question peuvent avoir différentes formes utiles pour retenir un milieu électrophorétique. Dans les conditions d'une électrophorèse, ces microcanaux permettent de diminuer sensiblement le flux électro-osmotique et/ou l'absorption par comparaison avec le verre de silice. De ce fait, ils sont utiles dans différentes applications électrophorétiques où des entités chargées se déplacent à travers un milieu sous l'influence d'un champ électrique appliqué.

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