Actinomadura chromoprotein, apoprotein, and gene cluster

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/31 (2006.01) A61K 38/16 (2006.01) A61P 31/04 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C07K 14/195 (2006.01) C12N 1/21 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/79 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2587285

The present invention provides a chromoprotein produced by Actinomadura sp. 21G792, as well as amino acid and nucleic acid sequences of the apoprotein component of the chromoprotein and of components of the biosynthetic pathway for the chromophore. The present invention is useful for developing pharmaceutical and treating diseases such as cancer or bacterial infections.

L'invention concerne une chromoprotéine produite par Actinomadura sp. 21G792, des séquences d'acide aminé et d'acide nucléique de la composante apoprotéine de la chromoprotéine et des composants de la voie biosynthétique du chromophore. L'invention sert au développement de compositions pharmaceutiques et au traitement de maladies telles que le cancer et les infections bactériennes.

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