Activatable particles, preparations and uses.

A - Human Necessities – 61 – K

Patent

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Details

A61K 51/12 (2006.01) A61K 9/14 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2564197

The invention relates to activatable novel particles which can be used in the health sector. The invention more particularly relates to composite particles which can generate free radicals or heat when excited by X-rays. The invention also relates to the uses thereof in human health. The inventive particles comprise an inorganic-based, and optionally organic-based, nucleus and can be activated in vivo in order to mark or affect cells, tissue or organs. The invention further relates to methods for the production of said particles, and pharmaceutical or diagnostic compositions containing them.

La présente invention concerne de nouvelles particules activables utilisables dans le domaine de la santé. Elle concerne notamment des particules composites capables de générer des radicaux libres ou de la chaleur sous excitation aux rayons X, et leurs utilisations en santé, notamment humaine. Les particules de l'invention comprennent un noyau à base de composés inorganiques et, éventuellement organique, et elles peuvent être activées in vivo, pour marquer ou altérer des cellules, tissus ou organes. L'invention concerne également des méthodes de production de telles particules, ainsi que des compositions pharmaceutiques ou diagnostiques les contenant.

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