Activated protein c formulations

Details Activated protein c formulations Activated protein c formulations

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2288143

The present invention relates to pharmaceutical formulations of activated protein C which also comprises sucrose, sodium chloride and sodium citrate buffer at a pH between about 5.5 and about 6.5. The activated protein C formulations of the present invention are more stable than other formulations of activated protein C and demonstrate fewer degradation products over time.

Ces formulations pharmaceutiques à base de protéine C activée comportent également du sucrose, du chlorure de sodium et un tampon citrate de sodium dont le pH se situe entre environ 5,5 et 6,5. Les formulations à base de protéine C activée de la présente invention sont plus stables que d'autres formulations de protéine C activée et donnent à terme moins de produits de dégradation.

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