Activating agent of stem cells and/or progenitor cells

Details Activating agent of stem cells and/or progenitor cells Activating agent of stem cells and/or progenitor cells

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) C12N 5/071 (2010.01) C12N 5/0775 (2010.01) A61K 35/12 (2006.01) C12N 9/74 (2006.01)

Patent

CA 2623950

The present invention provides an activating agent of stem cells and/or progenitor cells comprising a thrombin-like enzyme which can be used in regenerative medicine, and particularly in regenerative medicine utilizing self-regeneration, acting promptly and moderately depending on the state of advancement and the degree of injured organs and/or tissues to which regenerative medicine is applied, with few or no side effects. The present invention also provides a method for activating stem cells and/or progenitor cells in an animal comprising the step of administering to the animal an effective amount of a thrombin-like enzyme and use of the thrombin-like enzyme for activating stem cells and/or progenitor cells.

La présente invention concerne un agent activateur de cellules souches et/ou de cellules progéniteurs comprenant une enzyme de type thrombine qui peut être utilisé en médecine régénérative et notamment dans la médecine régénérative utilisant l'autorégénération qui agit rapidement et modérément en fonction de l'état de progression de la maladie et du degré d'endommagement des organes et/ou des tissus auxquels est appliquée la médecine régénérative, avec peu d'effets secondaires ou même aucun. Cette invention porte également sur une méthode d'activation des cellules souches et/ou des cellules progéniteurs chez un animal qui comprend les étapes suivantes: l'administration à l'animal d'une quantité efficace d'une enzyme de type thrombine et l'utilisation de ladite enzyme de type thrombine pour activer les cellules souches et/ou les cellules progéniteurs.

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