Activation and expansion of cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 5/0783 (2010.01) A61K 39/00 (2006.01) C12M 3/00 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2459587

The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.

De manière générale, la présente invention concerne des méthodes d'activation et de développement de cellules. Plus particulièrement, elle concerne une nouvelle méthode destinée à activer et/ou stimuler des cellules et permettant de maximiser le développement de ces cellules afin d'obtenir des densités extrêmement élevées. Dans les divers modes de réalisation de l'invention, les cellules sont activées et développées pour l'obtention de densités très élevées en peu de temps. Dans certains modes de réalisation, ces cellules sont activées et développées pour l'obtention d'un nombre très élevé de cellules en peu de temps. L'invention concerne également des compositions de cellules activées et développées selon les méthodes susmentionnées.

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