Activation and protection of cytotoxic lymphocytes using a...

Details Activation and protection of cytotoxic lymphocytes using a... Activation and protection of cytotoxic lymphocytes using a...

A - Human Necessities

61

K

A61K 31/03 (2006.01) A61K 31/352 (2006.01) A61K 38/19 (2006.01) A61K 39/39 (2006.01) A61K 45/06 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2377247

Methods and compositions for activating and protecting cytotoxic lymphocytes in the presence of monocytes (MO), comprising identifying a subject in need of enhanced cytotoxic lymphocyte activity; and administering to the patient an amount of diphenylionodonium (DPI), effective to activate and protect cytotoxic lymphocyte function in the presence of MO.

L'invention concerne des méthodes et des compositions permettant d'activer et de protéger des lymphocytes cytotoxiques en présence de monocytes (MO), les méthodes de cette invention consistant tout d'abord à identifier un sujet nécessitant une activation renforcée des lymphocytes cytotoxiques. Ces méthodes consistent ensuite à administrer à ce patient une quantité de diphénylionodonium (DPI) efficace pour activer et protéger les fonctions des lymphocytes cytotoxiques en présence de MO.

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