Activation-dependent protein expressed on the surface of...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 38/43 (2006.01) A61K 38/58 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 14/705 (2006.01) C07K 14/745 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 16/36 (2006.01) G01N 33/555 (2006.01) G01N 33/577 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2120622

2120622 9307174 PCTABS00021 The present invention provides a thrombin-activated platelet protein (TAPP). The protein is selectively expressed on the surface of thrombin-activated platelets. Antibodies which selectively bind to the thrombin-activated platelet protein are also provided. These compositions find use in the detection and treatment of blood clots.

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