Activator for peroxisome proliferator-activated receptor

Details Activator for peroxisome proliferator-activated receptor Activator for peroxisome proliferator-activated receptor

C - Chemistry, Metallurgy

07

D

C07D 277/28 (2006.01) A61K 31/496 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2609446

A compound represented by the general formula below or a salt thereof which can be used as an activator for PPAR. [Chemical formula] wherein W2 represents a bond, C(=O) or CH2; Z2 represents an oxygen or sulfur atom; R21, R22 and R23 independently represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms; a halogen atom, an alkyl group having 1 to 8 carbon atoms and substituted by a halogen atom or the like; and R24 and R25 independently represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms or an alkyl group having 1 to 8 carbon atoms and substituted by a halogen atom.

Composé représenté par la formule générale ci-dessous ou l~un de ses sels que l~on peut utiliser comme activateur pour le PPAR. [Formule chimique] où W2 représente une liaison, C(=O) ou CH2; Z2 représente un atome d~oxygène ou de soufre; R21, R22 et R23 représentent indépendamment un atome d~hydrogène, un groupe alkyle ayant de 1 à 8 atomes de carbone, un groupe alcoxy ayant de 1 à 8 atomes de carbone; un atome d~halogène, un groupe alkyle ayant de 1 à 8 atomes de carbone et substitué par un atome d~halogène ou similaire; et R24 et R25 représentent indépendamment un atome d~hydrogène, un groupe alkyle ayant de 1 à 8 atomes de carbone ou un groupe alkyle ayant de 1 à 8 atomes de carbone et substitué par un atome d~halogène.

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