C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2395344
The invention provides methods and compositions relating to polypeptide activators of caspases such as polypeptide and polynucleotide sequences diagnostic of caspase activators. These sequences and polypeptides and polynucleotides embodying these sequences find a wide variety of diagnostic and therapeutic applications involving detecting and/or modulating expression and/or function of activators or caspases or genes or transcripts encoding such activators and generating genetic and immuno probes specific to activators of caspases.
L'invention concerne des procédés et des compositions se rapportant à des activateurs polypeptidiques de caspases, notamment l'analyse des séquences polypeptidiques et polynucléotidiques des activateurs de caspases. Ces séquences, ainsi que les polynucléotides et polypeptides formant ces séquences, trouvent un large éventail d'applications diagnostiques et thérapeutiques qui comprennent la détection et/ou la modulation de l'expression et/ou de la fonction des activateurs ou des caspases, ou des gènes ou produits de transcription codant pour ces activateurs, et la production de sondes génétiques et immunologiques spécifiques de ces activateurs de caspases.
Du Chunying
Wang Xiaodong
Battison Williams Dupuis
Board Of Regents The University Of Texas System
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