Activators of executioner procaspases 3, 6 and 7

Details Activators of executioner procaspases 3, 6 and 7 Activators of executioner procaspases 3, 6 and 7

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/353 (2006.01) A61K 31/357 (2006.01) A61K 31/36 (2006.01) A61K 31/443 (2006.01) A61K 31/4433 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 311/12 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2711603

The present invention provides compounds as activators of procaspases 3, 6 and/or 7 and related derivatives, pharmaceutical compositions thereof, methods for their use, and methods for preparing these compounds. In one aspect, the compounds are useful for treating cancers and neoplastic diseases.

L'invention concerne des composés en tant qu'activateurs de procaspases 3, 6 et/ou 7 et dérivés associés, leurs compositions pharmaceutiques, des procédés pour leur utilisation, et des procédés de préparation de ces composés. Dans un aspect, les composés sont utiles pour le traitement du cancer et des pathologies néoplasiques.

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