Active agent delivery systems and methods for protecting and...

Details Active agent delivery systems and methods for protecting and... Active agent delivery systems and methods for protecting and...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 47/42 (2006.01) C07K 1/02 (2006.01)

Patent

CA 2420590

A composition comprising a polypeptide and an active agent covalently attached to the polypeptide. Also provided is a method for delivery of an active agent to a patient comprising administering to the patient a composition comprising a polypeptide and an active agent covalently attached to the polypeptide. Also provided is a method for protecting an active agent from degradation comprising covalently attaching the active agent to a polypeptide. Also provided is a method for controlling release of an active agent from a composition comprising covalently attaching the active agent to the polypeptide (Figure 1).

L'invention concerne une composition comprenant un polypeptide et un agent actif lié de manière covalente audit polypeptide. L'invention porte également sur un procédé de libération d'un agent actif dans un patient, qui consiste à administrer au patient une composition comprenant un polypeptide et un agent actif lié de manière covalente audit polypeptide. Par ailleurs, l'invention se rapporte à un procédé de protection d'un agent actif contre la dégradation, qui consiste à fixer de manière covalente l'agent actif à un polypeptide. Elle porte encore sur un procédé de régulation de la libération d'un agent actif d'une composition, qui consiste à fixer de manière covalente l'agent actif au polypeptide.

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