Active agent formulations, methods of making, and methods of...

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 9/14 (2006.01) A61K 31/216 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2656277

Active agent compositions comprising active agent particles having an effective average particle size of less than 2000 ran, wherein the compositions comprise a particle sequestrant are disclosed. Compositions having an effective average particle size of less than 2000 nm, wherein the compositions comprise no added surfactants, phospholipids, or combinations thereof, are also disclosed. In some embodiments, the active agent is fenofibrate. In other embodiments, the fenofibrate compositions are in a treatment form that that is bioequivalent to TriCor® 145 mg or 48 mg.

Compositions d'agent actif à particules d'agent actif de taille de particule effective moyenne inférieure à 2 000 ran, sachant que les compositions comportent un séquestrant de particule. Également, compositions à taille de particule effective moyenne inférieure à 2 000 nm, sachant que les compositions sont sans tensioactifs ajoutés, phospholipides, ou combinaisons correspondantes. Selon certaines variantes, l'agent actif est fénofibrate. Selon d'autres variantes, les compositions de fénofibrate se présentent sous une forme de traitement équivalant à TriCor® 145 mg ou 48 mg.

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