A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/36 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2689482
Active agents, compositions, and methods for inhibiting and reversing platelet function are provided herein. In particular embodiments, the active agents provided herein inhibit or reverse platelet function. In particular embodiments, the compositions described herein are pharmaceutical formulations. Methods of inhibiting and reversing platelet function are also provided herein. In particular embodiments, methods as described herein include administration of a Sema3E polypeptide. Further, methods of treating pathologic conditions associated with platelet function (i.e., platelet activation) and methods of screening active agent candidates are also provided.
La présente invention concerne des agents actifs, des compositions, et des procédés d'inhibition et d'inversion de la fonction plaquettaire. La présente invention concerne notamment des agents actifs qui inhibent ou inversent la fonction plaquettaire. La présente invention concerne en particulier des procédés qui comprennent l'administration d'un polypeptide Sema3E. La présente invention concerne en outre des procédés de traitement de conditions pathologiques associées à la fonction plaquettaire (en d'autres termes, l'activation plaquettaire) et des procédés de criblage d'agents actifs candidats.
Li Dean Y.
Smith Matthew
Weyrich Andy
Ridout & Maybee Llp
University Of Utah Research Foundation
LandOfFree
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