Active compound release systems

Details Active compound release systems Active compound release systems

A - Human Necessities

61

K

167/159

A61K 9/70 (2006.01)

Patent

CA 1229044

Active compound release systems ABSTRACT In a therapeutic system such as a plaster for administration of an active compound through the skin and comprising a covering layer which is essentially impermeable to the active compound, an active compound reservoir layer and a protective layer which can be pulled off and which is essentially impermeable to the active compound, the improvement wherein the reservoir layer contains about 1 - 30% of active compound in an elastomer mixture comprising a diene rubber which can optionally be copolymerised with an ?-olefin, mixed with from 0 up to about 70% by weight of a polyisobutylene, polybutadiene oil and/or paraffin oil, and a tackifying resin. Thereby the active compound can be released in regulated relatively large quantity over a prolonged period of time.

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