C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
167/220, 260/242
C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/6561 (2006.01) C07F 9/6571 (2006.01)
Patent
CA 2017648
B2754/Abs Abstract The (R)-isomer or the (S)-isomer of a compound of formula (IA), optionally in admixture with up to 45% of the mixture by weight of the corresponding (S)-isomer or the (R)-isomer respectively: Image (IA) wherein R11 is hydroxy or amino; R21 is amino or hydrogen; R31 is hydroxymethyl or acyloxymethyl; and R4 is a group of formula: Image wherein R5 and R6 are independently selected from hydrogen, C1-6 alkyl and optionally substituted phenyl; or R3 and R4 together are: B2754/Abs Image wherein R6 is as defined above; having antiviral activity, a process for their preparation and their use in the treatment of viral infections or neoplastic diseases.
Duckworth David M.
Harnden Michael R.
Beecham Group P.l.c.
Borden Ladner Gervais Llp
Duckworth David M.
Harnden Michael R.
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