Active compounds

C - Chemistry – Metallurgy – 07 – F

Patent

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167/220, 260/242

C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/6561 (2006.01) C07F 9/6571 (2006.01)

Patent

CA 2017648

B2754/Abs Abstract The (R)-isomer or the (S)-isomer of a compound of formula (IA), optionally in admixture with up to 45% of the mixture by weight of the corresponding (S)-isomer or the (R)-isomer respectively: Image (IA) wherein R11 is hydroxy or amino; R21 is amino or hydrogen; R31 is hydroxymethyl or acyloxymethyl; and R4 is a group of formula: Image wherein R5 and R6 are independently selected from hydrogen, C1-6 alkyl and optionally substituted phenyl; or R3 and R4 together are: B2754/Abs Image wherein R6 is as defined above; having antiviral activity, a process for their preparation and their use in the treatment of viral infections or neoplastic diseases.

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